Red Medicine [1st Edition] #LOB-E043

Red Medicine [1st Edition] #LOB-E043 collector guide

About Red Medicine

Red Medicine is a Normal Spell Card, printed as LOB-E043 in Legend of Blue Eyes White Dragon (2002) as a Common. Legend of Blue Eyes White Dragon was the first booster set of the English Yu-Gi-Oh! Trading Card Game. It brought Blue-Eyes White Dragon, Dark Magician, Red-Eyes Black Dragon and the five pieces of Exodia to English-speaking players, so almost every card in it is a piece of the game's history. Ungraded, this printing ranks 172nd of the 454 Legend of Blue Eyes White Dragon cards we track. The top card is Blue-Eyes White Dragon at €968.32.

Version and identification

This guide covers the 1st Edition printing. The words "1st Edition" are printed below the artwork on the left; copies without them are the Unlimited printing and usually sell for less. Check the code printed below the artwork on the right: it should read LOB-E043. The E in LOB-E043 marks the European English printing. The North American printing uses a code without the letter, sometimes with a different card number, and has its own prices. It is the Common version. Commons have a plain name and no foil. Legend of Blue Eyes White Dragon has 3 other printings of Red Medicine: LOB-054 (€0.22), LOB-054 1st Edition (€1.68) and LOB-E043 (€1.51). Each has its own price, so match the code, edition and rarity exactly.

Price history

Today an ungraded copy of this printing sells for about €3.58 and a PSA 10 for €94.36. Our monthly prices for it go back to August 2026. The current price is its high point on our records. Of the 4 printings of Red Medicine we track, this is the most valuable ungraded. The cheapest is Legend of Blue Eyes White Dragon LOB-054 at €0.22. 1st Edition copies sell for about 2.4× the Unlimited printing (€3.58 against €1.51).

Grading and population

A PSA 10 sells for 26.4× the ungraded price. That gap is big enough that grading a sharp, well-centred copy can pay for itself. Early English Yu-Gi-Oh! cards often have off-centre cuts and wear on the dark brown back borders, which is why high grades are hard to reach.

Investment potential

In its favour: it comes from the 1st Edition run of an early English set, which will never be printed again. Against it: thin trading, so selling quickly can mean accepting a lower price. Past prices do not guarantee future ones. This is not financial advice.

Before you buy

Expect to pay around €3.58 for a clean ungraded copy; played copies sell for less. Ask the seller to show the code LOB-E043, the "1st Edition" text and the Common finish clearly in the photos, as listing titles often mix up printings. Cards from 2002 often show white wear on the back edges and corners, so ask for photos of the back before you buy.

Card details and image from YGOPRODeck. Yu-Gi-Oh! is a trademark of Konami; Search Cards is not affiliated with Konami.